| Also known as: |
CD70 |
| Other names: |
CD27 ligand, CD27 ligand, CD27-L, CD27-L, CD70 antigen, CD70 antigen, CD70 antigen, Ki-24 antigen, Tumor necrosis factor ligand superfamily member 7, member 7, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 7, CD70 antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD70 |
| Other gene names: |
CD27-L, CD27LG, Cd27l, Cd27l, Cd27lg, Cd70, Tnfsf7, Tnfsf7, Cd70 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
FR70 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD70 is not expressed on resting T and B lymphocytes but expression is induced on activation, Clone FR70 is reported to block the functions of CD70 and has been used to block the interactions between CD27 and CD70 , Interaction of CD70 with its ligand CD27 is reported to play an important role in T-cell co-stimulation and the regulation of T-dependant B-cell activation and antibody production, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 30-33kD type II transmembrane protein belonging to the TNF superfamily, CD70 This item recognises mouse CD70 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunoprecipitation (IP) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD70 |
| Short name: |
RAT ANTI MOUSE CD70 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD70 molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, Extracellular, protein binding, this GO :0002020 and protease binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding, this GO :0005102 : receptor binding, this GO :0005125 : cytokine activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, CD70 molecule |
| Identity: |
11937 |
| Gene: |
CD70 |
More about : CD70 |
| Long gene name: |
CD70 molecule |
| Synonyms gene: |
CD27LG TNFSF7 |
| Synonyms gene name: |
member 7 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD27L |
| Locus: |
19p13, 3 |
| Discovery year: |
1993-11-08 |
| GenBank acession: |
L08096 |
| Entrez gene record: |
970 |
| Pubmed identfication: |
8387892 8120384 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000181834 |