| Also known as: |
CD70 |
| Other names: |
CD27 ligand, CD27 ligand, CD27-L, CD27-L, CD70 antigen, CD70 antigen, CD70 molecule, Ki-24 antigen, Tumor necrosis factor ligand superfamily member 7, member 7, surface antigen CD70, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 7, CD70 antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD70 |
| Other gene names: |
CD27-L, CD27L, CD27L, CD27LG, CD27LG, CD70, TNFSF7, TNFSF7, CD70 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
Rat IgG2a |
| Clone: |
TAN 1-7 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, CD70 |
| Form/Appearance: |
FITC |
| Storage and shipping: |
Antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol has to added and the vial must be stored at -20°, C, Lyophilized antibodies may be transported at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage |
| Tested applications:: |
Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
IgG1), CD70 TAN 1-7) |
| Short name: |
(Mouse IgG1), Anti-Mouse CD70 (clone: TAN 1-7) FITC |
| Technique: |
Fluorescein, mouses, Mouse |
| Isotype: |
IgG1 |
| Label: |
FITC |
| Species: |
Mouses, Mouse |
| Alternative name: |
(Mouse IgG1), fluorecein, antibody to-Mouse CD70 molecule (clonality: TAN 1-7) |
| Alternative technique: |
murine |
| Alternative to gene target: |
CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, Extracellular, protein binding, this GO :0002020 and protease binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding, this GO :0005102 : receptor binding, this GO :0005125 : cytokine activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, CD70 molecule |
| Identity: |
11937 |
| Gene: |
CD70 |
More about : CD70 |
| Long gene name: |
CD70 molecule |
| Synonyms gene: |
CD27LG TNFSF7 |
| Synonyms gene name: |
member 7 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD27L |
| Locus: |
19p13, 3 |
| Discovery year: |
1993-11-08 |
| GenBank acession: |
L08096 |
| Entrez gene record: |
970 |
| Pubmed identfication: |
8387892 8120384 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000181834 |