| Also known as: |
CD283 |
| Other names: |
N/A, Toll-like receptor 3, toll-like receptor 3, toll-like receptor 3, toll-like receptor 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD283 |
| Other gene names: |
CD283, IIAE2, N/A, TLR3, TLR3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
7, TLR3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, Cell surface expression of TLR3 has been reported on MRC-5 fibroblasts This antibody has also been shown to suppress poly (I) : poly C mediated IFN beta production by these cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR3 is a member of the Toll-like receptor (TLR) family and functions as a receptor for double-stranded (ds) RNA, TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, This particular antibody might cross react with speacies outside of the listed ones, otherwise known as CD283, CD283 This item recognises human and canine TLR3, They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD283 |
| Short name: |
MOUSE Anti-HUMAN CD283 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD283 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11849 |
| Gene: |
TLR3 |
More about : TLR3 |
| Long gene name: |
toll like receptor 3 |
| Synonyms gene name: |
toll-like receptor 3 |
| Synonyms: |
CD283 |
| Locus: |
4q35, 1 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88879 |
| Entrez gene record: |
7098 |
| Pubmed identfication: |
9435236 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000160345 |
| Locus Specific Databases: |
TLR3base: Mutation registry for Influenza-associated encephalopathy LRG_117 |