| known also as: |
Anti-RABBIT ANTI HUMAN CD283 |
| known also as: |
RABBIT ANTI HUMAN CD283 |
| known also as: |
Lapin ANTI Homo sapiens CD283 |
| known also as: |
CD283 |
| Other names: |
N/A, Toll-like receptor 3, toll-like receptor 3, toll-like receptor 3, toll-like receptor 3 |
| Gene name: |
CD283 |
| Other gene names: |
CD283, IIAE2, N/A, TLR3, TLR3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD283 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and type I interferons, This item has been shown as suitable for use in IHC on EL4 cells @ 1ug/ml, _x000D__x000D_TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, a 103, acting through adaptor molecules such as MyD88 and TRAF6, and has been shown to recognise double-stranded (ds) viral RNA, expressed at high levels in the placenta and pancreas and also expressed by dendritic cells, including that of the Influenza A and West Nile virus, otherwise known as toll receptor 3, 8kDa member of the evolutionarily conserved toll-like receptor family (TLRs), CD283 This item recognises human CD283, _x000D_ |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistology - Frozen (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD283 |
| Short name: |
Anti-HUMAN CD283 |
| Alternative name: |
sapiens CD283, antibody to-H |
| Identity: |
11849 |
| Gene: |
TLR3 |
More about : TLR3 |
| Long gene name: |
toll like receptor 3 |
| Synonyms gene name: |
toll-like receptor 3 |
| Synonyms: |
CD283 |
| Locus: |
4q35, 1 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88879 |
| Entrez gene record: |
7098 |
| Pubmed identfication: |
9435236 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000160345 |
| Locus Specific Databases: |
TLR3base: Mutation registry for Influenza-associated encephalopathy LRG_117 |