| Also known as: |
CD282 |
| Other names: |
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2, toll-like receptor 2, toll/interleukin 1 receptor-like 4, toll/interleukin-1 receptor-like protein 4, toll-like receptor 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD282 |
| Other gene names: |
CD282, TIL4, TIL4, TLR2, TLR2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
1, TL2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Removal of sodium azide is recommended prior to use in functional studies, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR2 is a member of the Toll-like receptor (TLR) family and is expressed primarily by peripheral blood monocytes, TLR2 is reported to respond to a diverse range of bacterial cell wall components, TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone TL2, mediating the innate immune response in co-operation with MD-2, otherwise known as CD282, 1 is reported to block TLR2 function, CD282 This item recognises human TLR2, They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD282 |
| Short name: |
MOUSE Anti-HUMAN CD282 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD282 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11848 |
| Gene: |
TLR2 |
More about : TLR2 |
| Long gene name: |
toll like receptor 2 |
| Synonyms gene name: |
toll-like receptor 2 |
| Synonyms: |
TIL4 CD282 |
| Locus: |
4q31, 3 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88878 |
| Entrez gene record: |
7097 |
| Pubmed identfication: |
9435236 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000161525 |