| Also known as: |
CD282 |
| Other names: |
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2, toll-like receptor 2, toll/interleukin 1 receptor-like 4, toll/interleukin-1 receptor-like protein 4, toll-like receptor 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD282 |
| Other gene names: |
CD282, TIL4, TIL4, TLR2, TLR2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
1, TL2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TLR2 is a member of the Toll-like receptor (TLR) family and is expressed primarily by peripheral blood monocytes, TLR2 is reported to respond to a diverse range of bacterial cell wall components, TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone TL2, mediating the innate immune response in co-operation with MD-2, otherwise known as CD282, 1 is reported to block TLR2 function, CD282 This item recognises human TLR2, They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Functional Assay (FA), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD282 |
| Short name: |
MOUSE Anti-HUMAN CD282 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD282 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11848 |
| Gene: |
TLR2 |
More about : TLR2 |
| Long gene name: |
toll like receptor 2 |
| Synonyms gene name: |
toll-like receptor 2 |
| Synonyms: |
TIL4 CD282 |
| Locus: |
4q31, 3 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88878 |
| Entrez gene record: |
7097 |
| Pubmed identfication: |
9435236 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000161525 |