| Also known as: |
MDM2 |
| Other names: |
Double minute 2 protein, E3 ubiquitin protein ligase, E3 ubiquitin-protein ligase Mdm2, E3 ubiquitin-protein ligase Mdm2, HDM2 transcript variant MYO-1, HDM2 transcript variant MYO-18, HDM2 transcript variant MYO-20, HDM2 transcript variant MYO-24, HDM2 transcript variant MYO-25, HDM2 transcript variant MYO-26, HDM2 transcript variant MYO-32, HDM2 transcript variant MYO-4, Hdm2, MDM2 oncogene, MDM2 variant FB28, MDM2 variant FB30, Mdm2, Mdm2, Oncoprotein Mdm2, double minute 2, human homolog of, oncoprotein Mdm2, p53 E3 ubiquitin protein ligase homolog, p53 binding protein, p53-binding protein, p53-binding protein Mdm2, transformed 3T3 cell double minute 2, E3 ubiquitin-protein ligase Mdm2 isoform MDM2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MDM2 |
| Other gene names: |
ACTFS, HDMX, Hdm2, MDM2, hdm2, MDM2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
SMP14 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI, MDM2 is over expressed in a range of human malignancies, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, breast cancer and bladder cancer, including soft tissue sarcomas, which forms a complex with p53 leading to p53 inhibition, MDM2 This item recognises the 90kD MDM2 protein |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunohistology - Resin (IHC), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
MDM2 |
| Short name: |
MOUSE Anti-MDM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-MDM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6973 |
| Gene: |
MDM2 |
More about : MDM2 |
| Long gene name: |
MDM2 proto-oncogene |
| Synonyms gene name: |
E3 ubiquitin protein ligase , human homolog of, mouse double minute 2, p53 binding protein (mouse) Mdm2 p53 binding protein homolog (mouse) MDM2 proto-oncogene, p53-binding protein Mdm2, transformed 3T3 cell double minute 2 |
| Synonyms: |
HDM2 MGC5370 |
| Locus: |
12q15 |
| Discovery year: |
1993-12-10 |
| Entrez gene record: |
4193 |
| Pubmed identfication: |
1614537 16905769 |
| RefSeq identity: |
NM_006880 |
| Classification: |
Zinc fingers RANBP2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000142827 |