| Also known as: |
CD8 |
| Other names: |
CD8 antigen, CD8a molecule, Leu2 T-lymphocyte antigen, OKT8 T-cell antigen, T cell co-receptor, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T-cell antigen, alpha polypeptide (p32), T-cell surface glycoprotein CD8 alpha chain isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD8 |
| Other gene names: |
CD8, CD8A, Leu2, MAL, MAL, p32, CD8A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
LT8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
It is also expressed weakly on NK cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD8 antigen is a co-receptor for MHC Class I in conjunction with the T cell receptor, This particular antibody might cross react with speacies outside of the listed ones, and is important in the selection process of CD8+ MHC Class I restricted T cells, CD8 This item recognises the human CD8 cell surface glycoprotein expressed by a subset of peripheral blood T cells which express cytotoxic/suppressor activity |
| Form/Appearance: |
Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R |
| Storage and shipping: |
DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description: |
This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity, Cytotoxic T cells cluster differentiators for flow cytometry |
| Gene target: |
CD8:RPE |
| Short name: |
MOUSE Anti-HUMAN CD8:RPE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD8:RPE (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
1706 |
| Gene: |
CD8A |
More about : CD8A |
| Long gene name: |
CD8a molecule |
| Synonyms gene: |
CD8 |
| Synonyms gene name: |
CD8 antigen, alpha polypeptide (p32) T-cell surface glycoprotein CD8 alpha chain |
| Locus: |
2p11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
925 |
| Pubmed identfication: |
1541829 |
| RefSeq identity: |
NM_001768 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130265 |
| Locus Specific Databases: |
CD8Abase: Mutation registry for CD8 deficiency LRG_44 |