| Also known as: |
C3c |
| Other names: |
ASP, Alternative name(s):, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Cleaved into the following 11 chains:Complement C3 beta chainComplement C3 alpha chainC3a anaphylatoxinAcylation stimulating protein, C3a anaphylatoxin, C3adesArg, Complement C3, acylation-stimulating protein cleavage product, complement C3, complement component 3, complement component C3, complement component C3a, complement component C3b, prepro-C3, complement C3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
C3c |
| Other gene names: |
AHUS5, ARMD9, ASP, ASP, C3, C3a, C3b, CPAMD1, CPAMD1, C3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
10-02A |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
C3b is further degraded into iC3b and C3dg/C3d, C3c is generated over the course of complement activation, C3dg and C3f, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D_, _x000D__x000D_C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation, iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha' chain fragment 1 + alpha' chain fragment 2), present in blood serum, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a, C3c This item recognises 135kDa complement component 3c (C3c) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
C3c |
| Short name: |
MOUSE Anti-HUMAN C3c Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens C3c (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |