| known also as: |
Anti-SHEEP ANTI HUMAN C3c |
| known also as: |
Ovine ANTI HUMAN C3c |
| known also as: |
Ovinae ANTI Homo sapiens C3c |
| known also as: |
C3c |
| Other names: |
ASP, Alternative name(s):, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Cleaved into the following 11 chains:Complement C3 beta chainComplement C3 alpha chainC3a anaphylatoxinAcylation stimulating protein, C3a anaphylatoxin, C3adesArg, Complement C3, acylation-stimulating protein cleavage product, complement C3, complement component 3, complement component C3, complement component C3a, complement component C3b, prepro-C3, complement C3 |
| Gene name: |
C3c |
| Other gene names: |
AHUS5, ARMD9, ASP, ASP, C3, C3a, C3b, CPAMD1, CPAMD1, C3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Sheep |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
C3 plays a central role in the activation of the complement system, C3a anaphylatoxin is a mediator of local inflammatory process, C3b can bind covalently, Defects in C3 can result in susceptibility to pyogenic infection, It induces the contraction of smooth muscle, Processing of C3 by C3 convertase is the central reaction in both classical and alternative complement pathways, Then iC3b is slowly cleaved (possibly by factor I) to form C3c and C3dg, This antbody shows minimal reactivity with related serum proteins, _x000D_ _x000D_C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released, a polypeptide fragment which is present in C3, and help to initiate the complement cascade, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, potentially resulting in cellular apoptosis, resulting in C3a and C3b, to cell surface carbohydrates or immune aggregates, via its reactive thioester, C3c This item detects human Complement 3c |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 5 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Frozen (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
C3c |
| Short name: |
SHEEP ANTI HUMAN C3c Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens C3c (Antibody to), ovine antibody to H |
| Alternative technique: |
antibodies |