| Also known as: |
CD88 |
| Other names: |
C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin receptor, C5a ligand, C5a-R, N/A, complement component 5, complement component 5a receptor 1, receptor 1, C5a anaphylatoxin chemotactic receptor |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD88 |
| Other gene names: |
C5a-R, C5aR, C5aR, C5ar, C5ar1, C5r1, C5r1, Cd88, D7Msu1, C5ar1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
20/70 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD88 is expressed on granulocytes, Clone 20/70 has been reported to block the binding of the C5a to murine CD88, In mouse, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD88 molecule functions as a receptor for the complement component C5a, This particular antibody might cross react with speacies outside of the listed ones, a 45kD G-protein coupled cell surface receptor, monocytes and macrophages but not on resting or stimulated lymphocytes, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection, which is otherwise known as C5aR, CD88 This item recognises murine CD88 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD88 |
| Short name: |
RAT ANTI MOUSE CD88 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD88 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1338 |
| Gene: |
C5AR1 |
More about : C5AR1 |
| Long gene name: |
complement C5a receptor 1 |
| Synonyms gene: |
C5R1 |
| Synonyms gene name: |
complement component 5 receptor 1 (C5a ligand) complement component 5a receptor 1 |
| Synonyms: |
C5A C5AR CD88 |
| Locus: |
19q13, 32 |
| Discovery year: |
1991-12-04 |
| Entrez gene record: |
728 |
| Pubmed identfication: |
1612600 |
| RefSeq identity: |
NM_001736 |
| Classification: |
Complement component GPCRs Complement system CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000183504 |