| known also as: |
Anti-RABBIT ANTI HUMAN CD294 (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN CD294 (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens CD294 (N-TERMINAL) |
| known also as: |
CD294 |
| Other names: |
Chemoattractant receptor-homologous molecule expressed on Th2 cells, G protein-coupled receptor 44, G-protein coupled receptor 44, G-protein coupled receptor 44, PGD2 receptor, Prostaglandin D2 receptor 2, chemoattractant receptor-homologous molecule expressed on TH2 cells, prostaglandin D2 receptor 2, prostaglandin D2 receptor CRTH2, prostaglandin D2 receptor 2 |
| Gene name: |
CD294 |
| Other gene names: |
Crth2, Crth2, Grp45, Ptgdr2, Ptgdr2, Gpr44 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD294 may be a useful marker for Th2 cells, _x000D__x000D_CD294 is a G protein-coupled receptor which has a high affinity for prostaglandin D2 (PGD2), _x000D__x000D_CD294 is predominantly expressed on Th2 cells, _x000D__x000D_PGD2 is thought to contribute to bronchoconstriction, also known as chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) and GRP44, and CD294 may contribute to this disease, and enhances their function and signalling with a possible role in Th2 cell differentiation, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites, basophils and eosinophils, eosinophilia and mucus production in allergic asthma, CD294 This item recognises CD294 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD294 |
| Short name: |
Anti-HUMAN CD294 (N-TERMINAL) |
| Alternative name: |
sapiens CD294 (N-TERMINAL), antibody to-H |
| Identity: |
4502 |
| Gene: |
PTGDR2 |
More about : PTGDR2 |
| Long gene name: |
prostaglandin D2 receptor 2 |
| Synonyms gene: |
GPR44 |
| Synonyms gene name: |
G protein-coupled receptor 44 |
| Synonyms: |
CRTH2 CD294 DP2 |
| Synonyms name: |
chemoattractant receptor homologous molecule expressed on T helper type 2 cells |
| Locus: |
11q12, 2 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
AF118265 |
| Entrez gene record: |
11251 |
| Pubmed identfication: |
10036181 |
| RefSeq identity: |
NM_004778 |
| Classification: |
Prostaglandin (prostanoid) receptors CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000167796 |