| known also as: |
Anti-RABBIT ANTI HUMAN ASK1 (C-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN ASK1 (C-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens ASK1 (C-TERMINAL) |
| known also as: |
ASK1 |
| Other names: |
ASK-1, ASK-1, Apoptosis signal-regulating kinase 1, MAP/ERK kinase kinase 5, MAPK/ERK kinase kinase 5, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5, Mitogen-activated protein kinase kinase kinase 5, apoptosis signal regulating kinase 1, apoptosis signal-regulating kinase 1, mitogen-activated protein kinase kinase kinase 5, mitogen-activated protein kinase kinase kinase 5, mitogen-activated protein kinase kinase kinase 5 |
| Gene name: |
ASK1 |
| Other gene names: |
ASK-1, ASK1, ASK1, MAP3K5, MAPKKK5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, MEKK5, MAP3K5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis, TNF) and endoplasmic reticulum stress, _x000D__x000D_ASK1 is a serine/threonine kinase, _x000D__x000D_ASK1 is widely expressed in a variety of human tissues including the heart and pancreas, also known as MAP kinase kinase kinase (MAPKKK), and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e, ASK1 This item recognises human ASK1 (Apoptosis signal-regulating kinase 1) a 155kDa protein belonging to the protein kinase superfamily, g |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Frozen (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
ASK1 |
| Short name: |
Anti-HUMAN ASK1 (C-TERMINAL) |
| Alternative name: |
sapiens ASK1 (C-TERMINAL), antibody to-H |
| Identity: |
6857 |
| Gene: |
MAP3K5 |
More about : MAP3K5 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase 5 |
| Synonyms gene: |
MEKK5 |
| Synonyms: |
MAPKKK5 ASK1 |
| Synonyms name: |
apoptosis signal regulating kinase 1 |
| Locus: |
6q23, 3 |
| Discovery year: |
1997-11-14 |
| GenBank acession: |
U67156 |
| Entrez gene record: |
4217 |
| Pubmed identfication: |
9465908 |
| Classification: |
Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000015647 |
| Locus Specific Databases: |
The Globin Gene Server |