| known also as: |
Anti-RABBIT ANTI HUMAN MAP1LC3A/B (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN MAP1LC3A/B (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens MAP1LC3A/B (N-TERMINAL) |
| known also as: |
MAP1LC3A/B |
| Other names: |
Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1 light chain 3-like protein 2, MAP1A/MAP1B LC3 B, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B light chain 3 B, Microtubule-associated protein 1 light chain 3 beta, Microtubule-associated proteins 1A/1B light chain 3B, autophagy-related ubiquitin-like modifier LC3 B, microtubule-associated protein 1 light chain 3 beta, microtubule-associated proteins 1A/1B light chain 3B, microtubule-associated proteins 1A/1B light chain 3B |
| Gene name: |
MAP1LC3A/B |
| Other gene names: |
ATG8F, LC3B, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, MAP1ALC3, MAP1LC3B, MAP1LC3B-a, MAP1LC3B |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, _x000D_LC3-I is the cytosolic form of LC3, _x000D_This item recognises both the LC3-I and LC3-II forms of MAP1LC3A and MAP1LC3B, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with the autophagosome membrane, during the autophagy process, membrane-bound form LC3-II, ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy, which is converted into the active, MAP1LC3A/B This item specifically recognises an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunofluorescence (IF), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
MAP1LC3A/B |
| Short name: |
Anti-HUMAN MAP1LC3A/B (N-TERMINAL) |
| Alternative name: |
sapiens MAP1LC3A/B (N-TERMINAL), antibody to-H |
| Identity: |
6838 |
| Gene: |
MAP1LC3A |
More about : MAP1LC3A |
| Long gene name: |
microtubule associated protein 1 light chain 3 alpha |
| Synonyms: |
MAP1BLC3 MAP1ALC3 LC3 LC3A ATG8E |
| Locus: |
20q11, 22 |
| Discovery year: |
2000-06-29 |
| Entrez gene record: |
84557 |
| Pubmed identfication: |
8833088 17580304 |
| RefSeq identity: |
NM_181509 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000032306 |