| known also as: |
Anti-RABBIT ANTI HUMAN CD273 |
| known also as: |
RABBIT ANTI HUMAN CD273 |
| known also as: |
Lapin ANTI Homo sapiens CD273 |
| known also as: |
CD273 |
| Other names: |
B7 dendritic cell molecule, B7-DC, Butyrophilin B7-DC, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, Programmed cell death 1 ligand 2, butyrophilin B7-DC, programmed cell death 1 ligand 2, programmed cell death 1 ligand 2, programmed death ligand 2, programmed cell death 1 ligand 2 |
| Gene name: |
CD273 |
| Other gene names: |
B7-DC, B7DC, B7DC, Btdc, CD273, CD273, PD-1 ligand 2, PD-L2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1L2, PDCD1LG2, PDL2, PDL2, Programmed death ligand 2, bA574F11, 2, PDCD1LG2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD273 is a single-pass type 1 membrane protein belonging to the immunoglobulin receptor superfamily, It is expressed in dendritic cells, _x000D__x000D_CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, _x000D__x000D_CD273 is highly expressed in the tissues of the heart, also known as B7-DC and Programmed Death Ligand 2 (PD-L2), and is a ligand for CD279 (PD-1), and is particularly important in the maintenance of self tolerance, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells, liver, lung, placenta and pancreas, CD273 This item detects human CD273 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD273 |
| Short name: |
Anti-HUMAN CD273 |
| Alternative name: |
sapiens CD273, antibody to-H |
| Identity: |
18731 |
| Gene: |
PDCD1LG2 |
More about : PDCD1LG2 |
| Long gene name: |
programmed cell death 1 ligand 2 |
| Synonyms: |
PD-L2 Btdc PDL2 bA574F11, 2 CD273 B7-DC |
| Synonyms name: |
B7 dendritic cell molecule |
| Locus: |
9p24, 1 |
| Discovery year: |
2003-11-14 |
| GenBank acession: |
AF344424 |
| Entrez gene record: |
80380 |
| Pubmed identfication: |
11224527 |
| RefSeq identity: |
NM_025239 |
| Classification: |
Endogenous ligands CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019504 |