| known also as: |
Anti-RABBIT ANTI HUMAN CASPASE-1 (C-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN CASPASE-1 (C-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens CASPASE-1 (C-TERMINAL) |
| known also as: |
CASPASE-1 |
| Other names: |
CASP1 nirs variant 1, Caspase-1, ICE, IL-1 beta-converting enzyme, IL-1 beta-converting enzyme, IL-1BC, IL1B-convertase, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, apoptosis-related cysteine peptidase, apoptosis-related cysteine peptidase (interleukin 1, beta, beta, caspase 1, caspase 1, caspase-1, convertase, convertase), interleukin 1, interleukin 1-B converting enzyme, p45, caspase-1 isoform beta |
| Other gene names: |
CASP-1, CASP1, ICE, ICE, IL-1BC, IL1BC, IL1BC, IL1BCE, P45, CASP1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Caspase-1 is an intracellular cysteine protease, _x000D__x000D_Caspase-1 has been classified as an inflammatory, _x000D__x000D_MBS221844 detects a cleaved subunit band of approximately 21 kDa in human heart cell lysates (predicted precursor MWT 45, _x000D__x000D_This regulation of pro-inflammatory cytokines by Caspase-1 has made inhibitors of Caspase-1 a possible target for use as therapeutic drugs for the treatment of inflammatory diseases <, cell death gene (ced-3), due to its essential role in the cleavage of the inactive precursors of the cytokines IL-1beta and IL-18, elegans<, identified as a mammalian homologue to <, into their mature activated and secretable forms, otherwise known as IL-1Beta converting enzyme, rather than apoptotic caspase, (1, /I>, /sup>, 2)<, 2kDa), C, CASPASE-1 Recognises an epitope within the C-terminal region (CT) of human Caspase-1, I>, sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CASPASE-1 |
| Short name: |
Anti-HUMAN CASPASE-1 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens caspase-1 (C-TERMINAL) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
1499 |
| Gene: |
CASP1 |
More about : CASP1 |
| Long gene name: |
caspase 1 |
| Synonyms gene: |
IL1BC |
| Synonyms gene name: |
apoptosis-related cysteine peptidase , apoptosis-related cysteine peptidase (interleukin 1, apoptosis-related cysteine protease (interleukin 1, beta, beta, caspase 1, convertase) caspase 1, convertase) caspase 1 |
| Synonyms: |
ICE |
| Synonyms name: |
beta, caspase-1 interleukin 1, convertase |
| Locus: |
11q22, 3 |
| Discovery year: |
1992-05-07 |
| GenBank acession: |
U13697 |
| Entrez gene record: |
834 |
| Pubmed identfication: |
1373520 9250871 |
| RefSeq identity: |
NM_033292 |
| Classification: |
Caspase recruitment domain containing Caspases |
| Havana BLAST/BLAT: |
OTTHUMG00000048072 |