| known also as: |
Anti-RABBIT ANTI CASPASE-7 (C-TERMINAL) |
| known also as: |
RABBIT ANTI CASPASE-7 (C-TERMINAL) |
| known also as: |
Lapin ANTI CASPASE-7 (C-TERMINAL) |
| known also as: |
CASPASE-7 |
| Other names: |
Apoptotic protease Mch-3, CMH-1, Caspase-7, ICE-like apoptotic protease 3, ICE-like apoptotic protease 3, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, apoptotic protease MCH-3, caspase 7, caspase 7, caspase-7, caspase-7 isoform alpha |
| Other gene names: |
CASP-7, CASP-7, CASP7, CMH-1, ICE-LAP3, ICE-LAP3, LICE2, MCH3, MCH3, CASP7 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Evidence that activation of Caspase-7 occurs during cell death induced by the cytokine death receptors Fas/APO-1 and the receptor of tumour necrosis factor (TNFR-1), _x000D__x000D_Caspase-7, a 35kDa cysteine protease, a member of the ICE/Ced-3 subfamily, coupled with the fact that granzyme-B activated Caspase-7 cleaves the nuclear enzyme poly (ADP-ribose) polymerase (PARP), is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits, otherwise known as ICE-like Apoptotic Protease 3 (ICE-LAP3), suggests an important role for Caspase-7 in both cytokine-mediated and Granzyme-B mediated apoptosis pathways, CASPASE-7 This item recognises an epitope within the C-terminal region (CT) of Caspase-7 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CASPASE-7 |
| Short name: |
Anti-CASPASE-7 (C-TERMINAL) |
| Alternative name: |
antibody to-caspase-7 (C-TERMINAL) |