| known also as: |
Anti-RABBIT ANTI ORAI3 (N-TERMINAL) |
| known also as: |
RABBIT ANTI ORAI3 (N-TERMINAL) |
| known also as: |
Lapin ANTI ORAI3 (N-TERMINAL) |
| known also as: |
ORAI3 |
| Other names: |
ORAI calcium release-activated calcium modulator 3, Protein orai-3, Transmembrane protein 142C, protein orai-3, transmembrane protein 142C, protein orai-3 |
| Gene name: |
ORAI3 |
| Other gene names: |
ORAI3, TMEM142C, TMEM142C, ORAI3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
(CRAC) channels, CRAC channels are the main pathway for Ca<, ORAI3, Studies indicate that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2, _x000D__x000D_Antigen stimulation of immune cells triggers Ca<, _x000D__x000D_ORAI3 is one of two mammalian homologs of ORAI1, _x000D__x000D_This item is not expected to cross react with either ORAI1 or ORAI2, a 31, a four- transmembrane spanning protein that is an essential component of CRAC channels, along with ORAI1 and ORAI2, also known as Transmembrane protein 142C (TMEM142C), entry through Ca<, functions as a Ca<, influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT, plasma membrane channel that is gated through interactions with STIM1, release-activated Ca<, sensor, the store-activated endoplasmic reticulum Ca<, /sup>, /sup>, /sup>, /sup>, /sup>, /sup>, 2+<, 2+<, 2+<, 2+<, 2+<, 2+<, 5 kDa multi-pass membrane protein belonging to the ORAI family, ORAI3 This item recognises human ORAI3, sup>, sup>, sup>, sup>, sup>, sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Frozen (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
ORAI3 |
| Short name: |
Anti-ORAI3 (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-ORAI3 (N-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28185 |
| Gene: |
ORAI3 |
More about : ORAI3 |
| Long gene name: |
ORAI calcium release-activated calcium modulator 3 |
| Synonyms gene: |
TMEM142C |
| Synonyms gene name: |
transmembrane protein 142C |
| Synonyms: |
MGC13024 |
| Locus: |
16p11, 2 |
| Discovery year: |
2006-06-20 |
| GenBank acession: |
BC006126 |
| Entrez gene record: |
93129 |
| Pubmed identfication: |
16582901 26956485 26718630 23890118 |
| RefSeq identity: |
NM_152288 |
| Classification: |
ORAI calcium release-activated calcium modulators |
| Havana BLAST/BLAT: |
OTTHUMG00000176768 |