| Gene info: |
2 and 3 channels were equally inhibited by extracellular Ca++, All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, However, Larger molecular weight bands are sometimes seen in SDS-PAGE, Na+ currents through ORAI1, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, ORAI3 is one of two mammalian homologs to ORAI1, This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2, a recently identified four-transmembrane spanning protein that is an essential component of CRAC, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2, indicating that each have similar affinities for Ca++ within the selectivity filter, the store-activated endoplasmic reticulum Ca++ sensor, these may represent post-translationally modified ORAI 3, ORAI3 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels |
| Gene names: |
ORAI3 Antibody [1B4F1] : TMEM142C |
| Antibodie's label: |
unlabelled serum |
| Purity: |
ORAI3 Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
1B4F1 |
| Immunoglobulin: |
IgG2b |
| Antigen: |
A 19 amino acid synthetic peptide from near the carboxy terminus of human ORAI3 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
ORAI3 antibody can be used for detection of ORAI3 by Western blot at 2 ug/mL |
| Suspention, pH, azide: |
02% sodium azide, ORAI3 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for one year, ORAI3 monoclonal antibody can be stored at -20 grades C |
| Works with: |
Rat, Human |
| Omim nr: |
74732916 |
| Ncbi nr: |
Q9BRQ5 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
93129 |
| GENE symbol: |
ORAI3 |
| Antigene name: |
ORAI calcium release-activated calcium modulator 3 |
| Source: |
homo sapiens |
| Protein nr: |
Q9BRQ5 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
ORAI3 [1B4F1] |
| Short name: |
anti-ORAI3 Antibody [1B4F1] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-ORAI3 (Antibody to) [1B4F1] |
| Alternative technique: |
antibodies |
| Identity: |
3829 |
| Gene: |
FRA10A |
More about : FRA10A |
| Long gene name: |
folic acid type, fra(10)(q23, fragile site, rare, 2) , 3) or fra(10)(q24 |
| Locus: |
10q23, 2 , 3 or 10q24 |
| Discovery year: |
1986-01-01 |
| Pubmed identfication: |
15203205 |