| Also known as: |
DECTIN-2 |
| Other names: |
C-type (calcium dependent, C-type lectin domain family 4, C-type lectin domain family 6 member A, C-type lectin domain family 6 member A, C-type lectin superfamily member 10, C-type lectin superfamily member 10, DC-associated C-type lectin 2, Dendritic cell-associated C-type lectin 2, carbohydrate recognition domain) lectin, dectin-2, dendritic cell-associated C-type lectin 2, member n, natural killer complex lectin, superfamily member 10, C-type lectin domain family 6 member A isoform 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
Clec4n, Clec6a, Clec6a, Clecsf10, Clecsf10, DC-associated C-type lectin 2, Dectin-2, Dectin2, Nkcl, Clec4n |
| Gene name synonims: |
Clec4n, Clec6a, Clec6a, Clecsf10, Clecsf10, DC-associated C-type lectin 2, Dectin-2, Dectin2, Nkcl, Clec4n |
| Other gene names: |
Clec4n, Clec6a, Clec6a, Clecsf10, Clecsf10, DC-associated C-type lectin 2, Dectin-2, Dectin2, Nkcl, Clec4n |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
11E4, D2 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Clone D2, In mouse, Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, _x000D__x000D__x000D_The function of dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance, a type II transmembrane protein that is a member of the C-type lectin superfamily, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells, kupffer cells in the liver and alveolar macrophages in the lung, 11E4 does not stain brain microglia or meningeal macrophages, DECTIN-2 This item recognises mouse DC-associated C-type lectin-2 (Dectin-2) |
| Form/Appearance: |
FITC (Purified IgG - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Anti-FITC Antibody |
| Gene target: |
DECTIN-2: |
| Short name: |
RAT ANTI MOUSE DECTIN-2:FITC Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label: |
FITC |
| Alternative name: |
RAT antibody to MOUSE DECTIN-2:fluorecein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14556 |
| Gene: |
CLEC6A |
More about : CLEC6A |
| Long gene name: |
C-type lectin domain family 6 member A |
| Synonyms gene: |
CLECSF10 |
| Synonyms gene name: |
C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 10 C-type lectin domain family 6 |
| Synonyms: |
dectin-2 |
| Locus: |
12p13, 31 |
| Discovery year: |
2004-11-18 |
| GenBank acession: |
AY321309 |
| Entrez gene record: |
93978 |
| RefSeq identity: |
NM_001007033 |
| Classification: |
C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000168672 |