| Also known as: |
CD32 |
| Other names: |
CDw32, Fc fragment of IgG, Fc-gamma RII-a, Immunoglobulin G Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II-a, fc-gamma RII-a, fc-gamma-RIIa, fcRII-a, igG Fc receptor II-a, low affinity IIa, low affinity immunoglobulin gamma Fc region receptor II-a, receptor (CD32), low affinity immunoglobulin gamma Fc region receptor II-a isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD32 |
| Other gene names: |
CD32, CD32, CD32A, CDw32, FCG2, FCG2, FCGR2, FCGR2A, FCGR2A1, FCGR2A1, Fc-gamma-RIIa, FcGR, FcRII-a, IGFR2, IGFR2, IgG Fc receptor II-a, FCGR2A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
AT10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Clone AT10 blocks the binding of IgG to Fc gamma RII, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen mediates several functions including endocytosis, This particular antibody might cross react with speacies outside of the listed ones, a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), activation of secretion, cytotoxicity and immunomodulation, granulocytes and platelets, monocytes, CD32 This item recognises the human CD32 antigen, CD32 is expressed by B cells |
| Form/Appearance: |
FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Anti-FITC Antibody |
| Gene target: |
CD32: |
| Short name: |
MOUSE Anti-HUMAN CD32:FITC Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label: |
FITC |
| Alternative name: |
sapiens CD32:fluorecein (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
3618 |
| Gene: |
FCGR2B |
More about : FCGR2B |
| Long gene name: |
Fc fragment of IgG receptor IIb |
| Synonyms gene: |
FCG2 FCGR2 |
| Synonyms gene name: |
Fc fragment of IgG, low affinity IIb, low affinity IIb, receptor (CD32) , receptor for (CD32) Fc fragment of IgG |
| Synonyms: |
CD32 CD32B |
| Synonyms name: |
Fc gamma receptor IIb |
| Locus: |
1q23, 3 |
| Discovery year: |
1991-08-21 |
| GenBank acession: |
BC031992 |
| Entrez gene record: |
2213 |
| Pubmed identfication: |
2139735 |
| RefSeq identity: |
NM_004001 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000034470 |