| Long name: |
Biotin-Linked Antibody to Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) |
| Antigen: |
Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) |
| Other names: |
Kazal type 5, Kazal type 5, Kazal type 5, Lympho-epithelial Kazal-type-related inhibitor, Serine protease inhibitor Kazal-type 5, lympho-epithelial Kazal-type-related inhibitor, lymphoepithelial Kazal-type-related inhibitor, serine peptidase inhibitor, serine protease inhibitor, serine protease inhibitor Kazal-type 5, serine peptidase inhibitor |
| Gene name: |
SPINK5, Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) |
| Gene synonims: |
LEKTI, LEKTI, LETKI, NETS, NS, SPINK5, VAKTI, SPINK5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
SPINK5, This is an antibody designed to detect Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) |
| Purification method: |
Antigen Affinity method, Caprylic Acid Ammonium Sulfate Precipitation, etc, The most common purification methods used in the antibody production are Affinity Chromatography |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Western Blot (WB), Immunohistochemistry (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Gene target: |
Serine Peptidase Inhibitor Kazal 5 (SPINK5) |
| Short name: |
Anti- Serine Peptidase Inhibitor Kazal 5 (SPINK5) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Kazal classification 5) (Antibody to), Antibody to Serine Peptidase suppressor Kazal classification 5 (serine peptidase inhibitor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Extracellular, Kazal type 5, LEKTI and LETKI and NETS and NS and VAKTI, SPINK5 and IDBG-52343 and ENSG00000133710 and 11005, Spink5 and IDBG-144109 and ENSMUSG00000055561 and 72432, peptidase inhibitor activity, this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005938 and cell cortex and cellular component this GO :0009913 and epidermal cell differentiation and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030414 and peptidase inhibitor activity and molecular function this GO :0030855 and epithelial cell differentiation and biological process this GO :0035315 and hair cell differentiation and biological process this GO :0042640 and anagen and biological process this GO :0045087 and innate immune response and biological process this GO :0045580 and regulation of T cell differentiation and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050777 and negative regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097209 and epidermal lamellar body and cellular component this GO :1902572 and negative regulation of serine-type peptidase activity and biological process, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0030414 : peptidase inhibitor activity, this GO :0005515 : protein binding, this GO :0030414 : peptidase inhibitor activity, 43608 and IDBG-646193 and ENSBTAG00000019140 and 526637, serine peptidase inhibitor |
| Identity: |
15464 |
| Gene: |
SPINK5 |
More about : SPINK5 |
| Long gene name: |
Kazal type 5 , serine peptidase inhibitor |
| Synonyms gene name: |
Kazal type 5 , serine protease inhibitor |
| Synonyms: |
VAKTI LEKTI LETKI NETS NS FLJ21544 FLJ97536 FLJ97596 FLJ99794 DKFZp686K19184 |
| Synonyms name: |
lymphoepithelial Kazal-type-related inhibitor |
| Locus: |
5q32 |
| Discovery year: |
2001-03-30 |
| GenBank acession: |
AJ228139 |
| Entrez gene record: |
11005 |
| Pubmed identfication: |
10419450 |
| RefSeq identity: |
NM_001127698 |
| Classification: |
Kazal type , Serine peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000134305 |
| Locus Specific Databases: |
SPINK5base: Mutation registry for Netherton syndrome LRG_110 |