| known also as: |
Anti-RABBIT ANTI HUMAN xCT (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN xCT (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens xCT (N-TERMINAL) |
| known also as: |
xCT |
| Other names: |
(cationic amino acid transporter, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Cystine/glutamate transporter, Solute carrier family 7 member 11, amino acid transport system xc-, calcium channel blocker resistance protein CCBR1, cystine/glutamate transporter, member 11, solute carrier family 7, solute carrier family 7 (anionic amino acid transporter light chain, solute carrier family 7 member 11, xCT, xc- system), y+ system) member 11, cystine/glutamate transporter |
| Gene name: |
xCT |
| Other gene names: |
CCBR1, N/A, SLC7A11, xCT, SLC7A11 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
This heterodimer forms a Na+ independent amino acid transport system which leads to the uptake of extracellular L-cystine in conjunction to L-glutamate efflux, This system is thought to play an important role in the protection of neurons and activated macrophages against oxidative stress, _x000D__x000D_xCT is the receptor which mediates Kaposi's sarcoma herpesvirus (KSHV) cell fusion, via a disulfide bond, which forms a complex with the 4F2 heavy chain (CD98), xCT This item detects an epitope within the N-terminal (NT) of the cysteine/glutamate transporter xCT |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
xCT |
| Short name: |
Anti-HUMAN xCT (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens xCT (N-TERMINAL) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11059 |
| Gene: |
SLC7A11 |
More about : SLC7A11 |
| Long gene name: |
solute carrier family 7 member 11 |
| Synonyms gene name: |
member 11 , solute carrier family 7 (anionic amino acid transporter light chain, xc- system) |
| Synonyms: |
xCT |
| Locus: |
4q28, 3 |
| Discovery year: |
2000-06-02 |
| GenBank acession: |
AB026891 |
| Entrez gene record: |
23657 |
| Pubmed identfication: |
10206947 12763038 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000133396 |