| known also as: |
Anti-RABBIT ANTI IRF7 (C-TERMINAL) |
| known also as: |
RABBIT ANTI IRF7 (C-TERMINAL) |
| known also as: |
Lapin ANTI IRF7 (C-TERMINAL) |
| known also as: |
IRF7 |
| Other names: |
IRF-7, Interferon regulatory factor 7, N/A, interferon regulatory factor 7, interferon regulatory factor 7, interferon regulatory factor-7H, interferon regulatory factor 7 isoform a |
| Gene name: |
IRF7 |
| Other gene names: |
IRF-7, IRF-7H, IRF7, IRF7A, IRF7B, IRF7C, IRF7H, IRF7 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), This then stabilizes the IRF7 protein, _x000D__x000D_Multiple IRF7 transcript variants have been identified, a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection, although their individual functions have not yet been established, in turn leading to increased IFN production, which differentiate in response to IFNs and virus infection, IRF7 This item detects an epitope within the C-terminal (CT) of human interferon regulatory factor 7 (IRF7) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
IRF7 |
| Short name: |
Anti-IRF7 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-interferon regulatory factor 7 (C-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0019043 and establishment of viral latency and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032479 and regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032607 and interferon-alpha production and biological process this GO :0032608 and interferon-beta production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0034124 and regulation of MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0034127 and regulation of MyD88-independent toll-like receptor signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0039530 and MDA-5 signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0045655 and regulation of monocyte differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050776 and regulation of immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060340 and positive regulation of type I interferon-mediated signaling pathway and biological process this GO :2000110 and negative regulation of macrophage apoptotic process and biological process, IRF-7H and IRF7A and IRF7B and IRF7C and IRF7H, IRF7 and IDBG-17225 and ENSG00000185507 and 3665, Irf7 and IDBG-212081 and ENSMUSG00000025498 and 54123, nuclei, protein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000975 and regulatory region DNA binding and molecular function this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000982 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002819 and regulation of adaptive immune response and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000982 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000982 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, 96672 and IDBG-645560 and ENSBTAG00000047680 and 100125591, interferon regulatory factor 7 |
| Identity: |
6122 |
| Gene: |
IRF7 |
More about : IRF7 |
| Long gene name: |
interferon regulatory factor 7 |
| Locus: |
11p15, 5 |
| Discovery year: |
1996-11-13 |
| GenBank acession: |
U53830 |
| Entrez gene record: |
3665 |
| RefSeq identity: |
NM_001572 |
| Havana BLAST/BLAT: |
OTTHUMG00000132019 |