| Long name: |
ALEXA FLUOR 647 Conjugated, GI24 Polyclonal Antibody |
| Also known as: |
Anti-GI24 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GI24 |
| Specificity: |
This is a highly specific antibody against GI24 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SISP1/GI24 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
135 million nucleotides and comprises nearly 4, As with most trisomies, Chromosome 10 contains over 800 genes, GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22, PTEN is an important tumor suppressor gene located on chromosome 10 and, Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10, The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging, also known as SISP1 or PP2135, causes a genetic predisposition to cancer development known as Cowden syndrome, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain, trisomy 10 is rare and is deleterious, when defective, 1, 5% of the human genome, Platelet receptor GI24 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
SISP1 GI24 B7-H5 B7H5 VISTA PD-1H |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GI24 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GI24 |
| Short name: |
GI24 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GI24 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30085 |
| Gene: |
VSIR |
More about : VSIR |
| Long gene name: |
V-set immunoregulatory receptor |
| Synonyms gene: |
C10orf54 |
| Synonyms gene name: |
chromosome 10 open reading frame 54 |
| Synonyms name: |
stress induced secreted protein 1 V-domain Ig suppressor of T cell activation PDCD1 homolog |
| Locus: |
10q22, 1 |
| Discovery year: |
2005-10-06 |
| GenBank acession: |
AF193048 |
| Entrez gene record: |
64115 |
| Pubmed identfication: |
12975309 24691993 25279955 |
| RefSeq identity: |
NM_022153 |
| Classification: |
V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000018426 |