| Long name: |
GI24 Primary Polyclonal Antibody |
| Also known as: |
GI24 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GI24 |
| Specificity: |
This is a highly specific antibody against GI24 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SISP1/GI24 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
135 million nucleotides and comprises nearly 4, As with most trisomies, Chromosome 10 contains over 800 genes, GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22, PTEN is an important tumor suppressor gene located on chromosome 10 and, Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10, The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging, also known as SISP1 or PP2135, causes a genetic predisposition to cancer development known as Cowden syndrome, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain, trisomy 10 is rare and is deleterious, when defective, 1, 5% of the human genome, Platelet receptor GI24 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GI24_HUMAN, PP2135, Platelet receptor Gi24, SISP1, UNQ730/PRO1412, stress induced secreted protein 1, C10orf54 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GI24 |
| Short name: |
GI24 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GI24 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30085 |
| Gene: |
VSIR |
More about : VSIR |
| Long gene name: |
V-set immunoregulatory receptor |
| Synonyms gene: |
C10orf54 |
| Synonyms gene name: |
chromosome 10 open reading frame 54 |
| Synonyms: |
SISP1 GI24 B7-H5 B7H5 VISTA PD-1H |
| Synonyms name: |
stress induced secreted protein 1 V-domain Ig suppressor of T cell activation PDCD1 homolog |
| Locus: |
10q22, 1 |
| Discovery year: |
2005-10-06 |
| GenBank acession: |
AF193048 |
| Entrez gene record: |
64115 |
| Pubmed identfication: |
12975309 24691993 25279955 |
| RefSeq identity: |
NM_022153 |
| Classification: |
V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000018426 |