| Long name: |
ALEXA FLUOR 594 Conjugated, MYBPC3 Polyclonal Antibody |
| Also known as: |
Anti-MYBPC3 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MYBPC3 |
| Specificity: |
This is a highly specific antibody against MYBPC3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MYBPC3 |
| Gene ID Number: |
4607 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle, MHC and native thin filaments, MYBPC3 binds F-Actin, Mutations in the MYBPC3 gene lead mainly to truncation of the protein, Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction, The MYBPC3 gene maps to chromosome 11p11, a heart disorder characterized by ventricular hypertrophy, and modifies the activity of Actin-activated myosin ATPase, which often involves the interventricular septum and is usually asymmetric, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), 2, MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MYBP-C FHC |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
MYBPC3 |
| Short name: |
MYBPC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, cardiac (Antibody to), myosin binding protein C |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CMD1MM and CMH4 and FHC and LVNC10 and MYBP-C, Cytoplasm, MYBPC3 and IDBG-43206 and ENSG00000134571 and 4607, MYBPC3 and IDBG-637371 and ENSBTAG00000021707 and 767614, Mybpc3 and IDBG-190220 and ENSMUSG00000002100 and 17868, cardiac, metal ion binding, this GO :0001671 and ATPase activator activity and molecular function this GO :0002027 and regulation of heart rate and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005863 and striated muscle myosin thick filament and cellular component this GO :0006936 and muscle contraction and biological process this GO :0006942 and regulation of striated muscle contraction and biological process this GO :0007155 and cell adhesion and biological process this GO :0008016 and regulation of heart contraction and biological process this GO :0008307 and structural constituent of muscle and molecular function this GO :0014705 and C zone and cellular component this GO :0017022 and myosin binding and molecular function this GO :0030016 and myofibril and cellular component this GO :0030017 and sarcomere and cellular component this GO :0030049 and muscle filament sliding and biological process this GO :0031034 and myosin filament assembly and biological process this GO :0031432 and titin binding and molecular function this GO :0031672 and A band and cellular component this GO :0032036 and myosin heavy chain binding and molecular function this GO :0032781 and positive regulation of ATPase activity and biological process this GO :0032971 and regulation of muscle filament sliding and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045214 and sarcomere organization and biological process this GO :0046872 and metal ion binding and molecular function this GO :0055010 and ventricular cardiac muscle tissue morphogenesis and biological process this GO :0060048 and cardiac muscle contraction and biological process, this GO :0001671 : ATPase activator activity, this GO :0001671 : ATPase activator activity and also this GO :0003779 : actin binding and also this GO :0005515 : protein binding and also this GO :0008307 : structural constituent of muscle and also this GO :0017022 : myosin binding and also this GO :0031432 : titin binding and also this GO :0032036 : myosin heavy chain binding and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding, this GO :0003779 : actin binding, this GO :0005515 : protein binding, this GO :0008307 : structural constituent of muscle, this GO :0017022 : myosin binding, this GO :0031432 : titin binding, this GO :0032036 : myosin heavy chain binding, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, myosin binding protein C |
| Identity: |
7551 |
| Gene: |
MYBPC3 |
More about : MYBPC3 |
| Long gene name: |
cardiac , myosin binding protein C |
| Synonyms gene: |
CMH4 |
| Synonyms gene name: |
cardiac , myosin-binding protein C |
| Locus: |
11p11, 2 |
| Discovery year: |
1995-05-30 |
| GenBank acession: |
X84075 |
| Entrez gene record: |
4607 |
| Pubmed identfication: |
7744002 8358441 |
| Classification: |
I-set domain containing Myosin binding proteins Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166986 |
| Locus Specific Databases: |
FHC Mutation Database LRG_386 |