| Long name: |
Biotin-Linked Antibody to Forkhead Box Protein P3 (FOXP3) |
| Antigen: |
Forkhead Box Protein P3 (FOXP3) |
| Other names: |
FOXP3delta7, Forkhead box protein P3, Scurfin, X-linked, X-linked, enteropathy, enteropathy, forkhead box P3, forkhead box protein P3, immune dysregulation, immunodeficiency, polyendocrinopathy, polyendocrinopathy, scurfin, forkhead box protein P3 isoform b |
| Gene name: |
FOXP3, Forkhead Box Protein P3 (FOXP3) |
| Gene synonims: |
AIID, DIETER, FOXP3, IPEX, IPEX, JM2, PIDX, XPID, FOXP3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
FOXP3, This is an antibody designed to detect Forkhead Box Protein P3 (FOXP3) |
| Purification method: |
Antigen Affinity method, Caprylic Acid Ammonium Sulfate Precipitation, etc, The most common purification methods used in the antibody production are Affinity Chromatography |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Western Blot (WB), Immunohistochemistry (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
Forkhead Box Protein P3 (FOXP3) |
| Short name: |
Anti- Forkhead Box Protein P3 (FOXP3) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Antibody to Forkhead Box Protein P3 (forkhead box P3) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD25-positive, CD25-positive, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009615 and response to virus and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0031064 and negative regulation of histone deacetylation and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032713 and negative regulation of interleukin-4 production and biological process this GO :0032714 and negative regulation of interleukin-5 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0032792 and negative regulation of CREB transcription factor activity and biological process this GO :0032831 and positive regulation of CD4-positive, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046007 and negative regulation of activated T cell proliferation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048294 and negative regulation of isotype switching to IgE isotypes and biological process this GO :0048302 and regulation of isotype switching to IgG isotypes and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050710 and negative regulation of cytokine secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050777 and negative regulation of immune response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051525 and NFAT protein binding and molecular function, FOXP3 and IDBG-637186 and ENSBTAG00000013279 and 506053, FOXP3 and IDBG-66215 and ENSG00000049768 and 50943, Foxp3 and IDBG-128986 and ENSMUSG00000039521 and 20371, NFAT protein binding, alpha-beta regulatory T cell differentiation and biological process this GO :0002456 and T cell mediated immunity and biological process this GO :0002507 and tolerance induction and biological process this GO :0002513 and tolerance induction to self antigen and biological process this GO :0002637 and regulation of immunoglobulin production and biological process this GO :0002666 and positive regulation of T cell tolerance induction and biological process this GO :0002669 and positive regulation of T cell anergy and biological process this GO :0002677 and negative regulation of chronic inflammatory response and biological process this GO :0002725 and negative regulation of T cell cytokine production and biological process this GO :0002851 and positive regulation of peripheral T cell tolerance induction and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006355 and regulation of transcription, alpha-beta regulatory T cell differentiation and biological process this GO :0032914 and positive regulation of transforming growth factor beta1 production and biological process this GO :0033092 and positive regulation of immature T cell proliferation in thymus and biological process this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0035066 and positive regulation of histone acetylation and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0042036 and negative regulation of cytokine biosynthetic process and biological process this GO :0042110 and T cell activation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042826 and histone deacetylase binding and molecular function this GO :0043029 and T cell homeostasis and biological process this GO :0043234 and protein complex and cellular component this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045066 and regulatory T cell differentiation and biological process this GO :0045077 and negative regulation of interferon-gamma biosynthetic process and biological process this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001782 and B cell homeostasis and biological process this GO :0001816 and cytokine production and biological process this GO :0002262 and myeloid cell homeostasis and biological process this GO :0002361 and CD4-positive, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0003714 : transcription corepressor activity and also this GO :0005515 : protein binding and also this GO :0035035 : histone acetyltransferase binding and also this GO :0042803 : protein homodimerization activity and also this GO :0042826 : histone deacetylase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding and also this GO :0051059 : NF-kappaB binding and also this GO :0051525 : NFAT protein binding, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0003714 : transcription corepressor activity, this GO :0005515 : protein binding, this GO :0035035 : histone acetyltransferase binding, this GO :0042803 : protein homodimerization activity, this GO :0042826 : histone deacetylase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, this GO :0051059 : NF-kappaB binding, this GO :0051525 : NFAT protein binding, forkhead box P3 |
| Identity: |
6106 |
| Gene: |
FOXP3 |
More about : FOXP3 |
| Long gene name: |
forkhead box P3 |
| Synonyms gene: |
IPEX |
| Synonyms gene name: |
X-linked , enteropathy, immune dysregulation, polyendocrinopathy |
| Synonyms: |
JM2 XPID AIID PIDX DIETER SCURFIN |
| Locus: |
Xp11, 23 |
| Discovery year: |
2000-05-05 |
| Entrez gene record: |
50943 |
| Pubmed identfication: |
10677306 11138001 |
| RefSeq identity: |
NM_014009 |
| Classification: |
Forkhead boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000024135 |
| Locus Specific Databases: |
FOXP3base: Mutation registry for Immunodysregulation, IPEX Mental Retardation database LRG_62 , X-linked, and enteropathy, polyendocrinopathy |