| Long name: |
Cy5 Conjugated, INTS3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
INTS3 |
| Specificity: |
This is a highly specific antibody against INTS3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
960-998/1043 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human INTS3 |
| Gene ID number: |
65123 |
| Swiss Prot: |
Q68E01 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Component of the SOSS complex, In the SOSS complex, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites, recombinational repair and maintenance of genomic stability, Component of the Integrator complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
FLJ21919 INT3 SOSS-A |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
INTS3 Conjugated |
| Short name: |
Conjugated, INTS3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, INTS3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
26153 |
| Gene: |
INTS3 |
More about : INTS3 |
| Long gene name: |
integrator complex subunit 3 |
| Synonyms gene: |
C1orf60 |
| Synonyms gene name: |
chromosome 1 open reading frame 60 |
| Synonyms name: |
sensor of single-strand DNA complex subunit A |
| Locus: |
1q21, 3 |
| Discovery year: |
2005-05-13 |
| GenBank acession: |
BX640950 |
| Entrez gene record: |
65123 |
| Pubmed identfication: |
16239144 |
| RefSeq identity: |
NM_023015 |
| Classification: |
Integrator complex |
| Havana BLAST/BLAT: |
OTTHUMG00000037089 |