| Long name: |
ALEXA FLUOR 647 Conjugated, FEZ1 Polyclonal Antibody |
| Also known as: |
Anti-FEZ1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FEZ1 |
| Specificity: |
This is a highly specific antibody against FEZ1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FEZ1 |
| Gene ID Number: |
9638 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
During cell-cycle progression, FEZ1 acts as a negative regulator of cell growth, FEZ1 is expressed in normal breast and prostate, FEZ1 localizes to microtubule components and is hyperphosphorylated by cAMP-dependent kinase, The 8p22-p21 region contains the FEZ1 gene, The FEZ1 protein (also known as leucine zipper putative tumor suppressor or LZTS1) contains a DNA-binding leucine zipper motif, The absence of FEZ1 expression is characteristic of breast and prostate cancer cell lines as well as primary breast and pro-state tumors, This absence of FEZ1 may be due to several factors, but alterations in FEZ1 expression result in abnormal cell growth, including mutations in the FEZ1 gene or hypermethylation of the CpG island flanking the FEZ1 promoter region, prostate and breast, which is altered in tumors of the esophagus, Frequent loss of heterozygosity (LOH) at human chromosome 8p22-p21 is associated with various tumors including prostate and breast cancer |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
UNC-76 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the FEZ1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
FEZ1 |
| Short name: |
FEZ1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, fasciculation and elongation protein zeta 1 (zygin I) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FEZ1 and IDBG-642679 and ENSBTAG00000009124 and 511751, FEZ1 and IDBG-75464 and ENSG00000149557 and 9638, Fez1 and IDBG-149600 and ENSMUSG00000032118 and 235180, Plasma membranes, protein N-terminus binding, this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005813 and centrosome and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0007155 and cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0042995 and cell projection and cellular component this GO :0043015 and gamma-tubulin binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0051654 and establishment of mitochondrion localization and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process, this GO :0005080 : protein kinase C binding, this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0043015 : gamma-tubulin binding and also this GO :0047485 : protein N-terminus binding, this GO :0005515 : protein binding, this GO :0043015 : gamma-tubulin binding, this GO :0047485 : protein N-terminus binding, fasciculation and elongation protein zeta 1 (zygin I) |
| Identity: |
3659 |
| Gene: |
FEZ1 |
More about : FEZ1 |
| Long gene name: |
fasciculation and elongation protein zeta 1 |
| Synonyms name: |
zygin I |
| Locus: |
11q24, 2 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
U60060 |
| Entrez gene record: |
9638 |
| Pubmed identfication: |
9096408 15843383 |
| RefSeq identity: |
NM_005103 |
| Havana BLAST/BLAT: |
OTTHUMG00000165886 |