| Long name: |
IFI35 Primary Polyclonal Antibody |
| Also known as: |
IFI35 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
I35 |
| Specificity: |
This is a highly specific antibody against I35 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IFI35 |
| Gene ID number: |
3430 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
IFI-35 (Interferon-induced 35 kDa protein), IFI-35 is a leucine zipper protein that can form homodimers, IFI-35 is unable to be degraded by the proteasome, Localized to the nucleus and expressed in macrophages, Once complexed with Nmi, Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), also known as IFP35, but, cannot bind DNA, fibroblasts and epithelial cells, is a 286 amino acid interferon-induced protein, resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events, thereby controlling various events within the cell, unlike most leucine zipper proteins, The Interferon family of proteins are able to alter the expression of a variety of target genes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
I35, IN35, IN35_HUMAN, Interferon induced 35 kDa protein, Interferon-induced 35 kDa protein, P 35, P35, i-35, I 35 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IFI35 |
| Short name: |
IFI35 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
interferon-induced protein 35 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IFI35 and IDBG-52075 and ENSG00000068079 and 3430, IFI35 and IDBG-640619 and ENSBTAG00000007389 and 510697, IFP35, Ifi35 and IDBG-212192 and ENSMUSG00000010358 and 70110, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, interferon-induced protein 35 |
| Identity: |
5399 |
| Gene: |
IFI35 |
More about : IFI35 |
| Long gene name: |
interferon induced protein 35 |
| Synonyms gene name: |
interferon-induced protein 35 |
| Synonyms: |
IFP35 |
| Locus: |
17q21, 31 |
| Discovery year: |
1996-04-12 |
| GenBank acession: |
BC001356 |
| Entrez gene record: |
3430 |
| RefSeq identity: |
NM_005533 |
| Havana BLAST/BLAT: |
OTTHUMG00000167720 |