| Long name: |
Frataxin Primary Polyclonal Antibody |
| Also known as: |
Frataxin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Frataxin |
| Specificity: |
This is a highly specific antibody against Frataxin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frataxin |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Coli human frataxin binds iron atoms at a rate of 10 iron atoms per 1 molecule of the frataxin polymer, Frataxin assembles into a stable homopolymer with iron-binding capabilities, Frataxin is expressed in tissues with high metabolic activity including heart, Frataxin may also function as an activator of oxidative phosphorylation to increase mitochondrial membrane potential and elevate cellular ATP, The human frataxin gene maps to chromosome 9q13, Thus, When expressed in E, frataxin appears to function in some capacity for iron-storage for the mitochondria, liver and brown fat, Friedreich ataxia is a progressive neurodegenerative disorder caused by loss of function mutations in the frataxin gene, The frataxin gene encodes a mitochondrial protein of the same name |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CyaY, FA antibody FARR, FRDA, FRDA_HUMAN, FXN, Frataxin mature form, Frataxin81-210, Friedreich ataxia protein, MGC57199, MSF01, MSF31, MSF42, d-FXN, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Frataxin |
| Short name: |
Frataxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Frataxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
51607 |
| Gene: |
FXNP2 |
More about : FXNP2 |
| Long gene name: |
frataxin pseuodgene 2 |
| Locus: |
9q33, 3 |
| Discovery year: |
2015-03-19 |
| Entrez gene record: |
100418706 |
| Havana BLAST/BLAT: |
OTTHUMG00000020666 |