| Long name: |
ALAS1 Primary Polyclonal Antibody |
| Also known as: |
ALAS1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ALAS1 |
| Specificity: |
This is a highly specific antibody against ALAS1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALAS1/ALAS-H |
| Gene ID number: |
211 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ALAS-E, ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells, NF-E2 and EKLF, Since the ALAS gene maps to the X chromosome, Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H, The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, The erythroid-specific isoenzyme, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver, 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
5 aminolevulinate synthase, 5 aminolevulinate synthase nonspecic mitochondrial, 5 aminolevulinic acid synthase, 5-aminolevulinate synthase, 5-aminolevulinic acid synthase 1, ALAS, ALAS 3, ALAS H, ALAS N, ALAS-H, ALAS3, ALASH, Alas 1, Aminolevulinate delta synthase 1, Aminolevulinic acid synthase 1, Delta ALA synthetase, Delta aminolevulinate synthase, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1, HEM1_HUMAN, MIG 4, MIG4, Migration inducing protein 4, alaS1, nonspecic, mitochondrial |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ALAS1 |
| Short name: |
ALAS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ALAS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
396 |
| Gene: |
ALAS1 |
More about : ALAS1 |
| Long gene name: |
5', -aminolevulinate synthase 1 |
| Synonyms gene: |
ALAS3 ALAS |
| Synonyms gene name: |
aminolevulinate, delta-, synthase 1 |
| Locus: |
3p21, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X56351 |
| Entrez gene record: |
211 |
| Havana BLAST/BLAT: |
OTTHUMG00000158108 |