| Long name: |
FITC Conjugated, FECH Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FECH |
| Specificity: |
This is a highly specific antibody against FECH |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human EPB41 |
| Gene ID number: |
2235 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in ferrochelatase are associated with protoporphyria, Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway), They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, They manifest with either skin problems, Two transcript variants encoding different isoforms have been found for this gene, and is localised in the mitochondrion, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors), or neurological complications, or occasionally both, Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FECH Conjugated |
| Short name: |
FITC Conjugated, FECH Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, FECH (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3647 |
| Gene: |
FECH |
More about : FECH |
| Long gene name: |
ferrochelatase |
| Synonyms gene name: |
ferrochelatase (protoporphyria) |
| Synonyms name: |
protoporphyria |
| Locus: |
18q21, 31 |
| Discovery year: |
1990-05-14 |
| GenBank acession: |
D00726 |
| Entrez gene record: |
2235 |
| Pubmed identfication: |
1838349 |
| Havana BLAST/BLAT: |
OTTHUMG00000132740 |
| Locus Specific Databases: |
LRG_1080 |