| Long name: |
ALEXA FLUOR 647 Conjugated, AMPK gamma 1/2/3 Polyclonal Antibody |
| Also known as: |
Anti-AMPK gamma 1/2/3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AMPK gamma 1/2/3 |
| Specificity: |
This is a highly specific antibody against AMPK gamma 1/2/3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
280-330/569 |
| Subcellular location: |
Cytoplasm, Nucleus, Extracellular |
| Source: |
³, 2, This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRKAG2/AMPKÎ |
| Gene ID Number: |
5571, 51422, 53632 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein, Human AMPKg2 and AMPKg3, It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways, The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, The human AMPKg1 gene encodes a 331 amino acid protein, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation, respectively, respectively, respectively, which are 569 and 492 amino acid proteins, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
AMPK AMPKa2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the AMPK gamma 1/2/3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
AMPK gamma 1/2/3 |
| Short name: |
AMPK gamma 1/2/3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, AMPK g 1/2/3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9377 |
| Gene: |
PRKAA2 |
More about : PRKAA2 |
| Long gene name: |
protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene: |
PRKAA |
| Synonyms gene name: |
AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Locus: |
1p32, 2 |
| Discovery year: |
1995-12-12 |
| GenBank acession: |
BC069823 |
| Entrez gene record: |
5563 |
| Pubmed identfication: |
7959015 |
| RefSeq identity: |
NM_006252 |
| Havana BLAST/BLAT: |
OTTHUMG00000008282 |