| Long name: |
ALEXA FLUOR 647 Conjugated, MARCH3 Polyclonal Antibody |
| Also known as: |
Anti-37681 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
37681 |
| Specificity: |
This is a highly specific antibody against 37681 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MARCH3 |
| Gene ID Number: |
115123 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Involved in the pathway of protein modification, MARCH3 (membrane-associated ring finger (C3HC4) 3), MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MGC48332 MARCH-III RNF173 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MARCH3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MARCH3 |
| Short name: |
MARCH3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, E3 ubiquitin protein ligase (Antibody to), membrane-associated ring finger (C3HC4) 3 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
E3 ubiquitin protein ligase, MARCH3 and IDBG-39523 and ENSG00000173926 and 115123, MARCH3 and IDBG-644898 and ENSBTAG00000006797 and 520348, March3 and IDBG-148017 and ENSMUSG00000032656 and 320253, Plasma membranes, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0006897 and endocytosis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0046872 and metal ion binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0046872 : metal ion binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0046872 : metal ion binding, membrane-associated ring finger (C3HC4) 3 |
| Identity: |
28728 |
| Gene: |
MARCH3 |
More about : MARCH3 |
| Long gene name: |
membrane associated ring-CH-type finger 3 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , membrane-associated ring finger (C3HC4) 3 membrane-associated ring finger (C3HC4) 3 |
| Locus: |
5q23, 2 |
| Discovery year: |
2005-01-26 |
| GenBank acession: |
AF055007 |
| Entrez gene record: |
115123 |
| Pubmed identfication: |
14722266 8619474 |
| RefSeq identity: |
NM_178450 |
| Classification: |
Membrane associated ring-CH-type fingers Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000128968 |