| Long name: |
FITC Conjugated, SASS6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SASS6 |
| Specificity: |
This is a highly specific antibody against SASS6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SASS6 |
| Gene ID number: |
163786 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6, Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole, LK4, SAS-6, SAS-6 associates only transiently with nascent procentrioles, SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain, SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation, SAS-6 levels oscillate during the cell cycle, The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation, and it accumulates again at the end of the following G1 phase, it is degraded in mitosis starting at anaphase, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles, SAS-6 (spindle assembly abnormal protein 6 homolog |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DKFZp761A078 SAS-6 FLJ22097 SAS6 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SASS6 Conjugated |
| Short name: |
FITC Conjugated, SASS6 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SASS6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
25403 |
| Gene: |
SASS6 |
More about : SASS6 |
| Long gene name: |
SAS-6 centriolar assembly protein |
| Synonyms gene name: |
elegans) , spindle assembly 6 homolog (C |
| Locus: |
1p21, 2 |
| Discovery year: |
2005-10-13 |
| GenBank acession: |
AL834265 |
| Entrez gene record: |
163786 |
| Pubmed identfication: |
15665853 14654843 |
| RefSeq identity: |
NM_194292 |
| Havana BLAST/BLAT: |
OTTHUMG00000010754 |