| Long name: |
MLF1 Primary Polyclonal Antibody |
| Also known as: |
MLF1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MLF1 |
| Specificity: |
This is a highly specific antibody against MLF1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MLF1/2/3 |
| Gene ID number: |
4291 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus, Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels, Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest, Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MLF1, MLF1_HUMAN, MLF2, MLF3, Myelodysplasia myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1, myeloid leukemia factor 1 variant 1, myeloid leukemia factor 1 variant 2, myeloid leukemia factor 1 variant 3, Hls7 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MLF1 |
| Short name: |
MLF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
myeloid leukemia factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0019904 and protein domain specific binding and molecular function, MLF1 and IDBG-63091 and ENSG00000178053 and 4291, MLF1 and IDBG-637188 and ENSBTAG00000004126 and 533379, Mlf1 and IDBG-150128 and ENSMUSG00000048416 and 17349, nuclei, protein domain specific binding, this GO :0002318 and myeloid progenitor cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0005515 : protein binding and also this GO :0019904 : protein domain specific binding, this GO :0005515 : protein binding, this GO :0019904 : protein domain specific binding, myeloid leukemia factor 1 |
| Identity: |
7125 |
| Gene: |
MLF1 |
More about : MLF1 |
| Long gene name: |
myeloid leukemia factor 1 |
| Synonyms name: |
myeloid leukemia factor 1 variant 1 myeloid leukemia factor 1 variant 2 myeloid leukemia factor 1 variant 3 |
| Locus: |
3q25, 32 |
| Discovery year: |
1994-08-29 |
| GenBank acession: |
L49054 |
| Entrez gene record: |
4291 |
| Pubmed identfication: |
8570204 |
| RefSeq identity: |
NM_022443 |
| Havana BLAST/BLAT: |
OTTHUMG00000158775 |