| Long name: |
FITC Conjugated, COPS6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
COPS6 |
| Specificity: |
This is a highly specific antibody against COPS6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human COPS6 |
| Gene ID number: |
10980 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CSA or DDB2, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, Has some glucocorticoid receptor-responsive activity, ITPK1 and IRF8, IkappaBalpha/NFKBIA, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, The complex is also involved in phosphorylation of p53/TP53, a complex involved in various cellular and developmental processes, c-jun/JUN, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, possibly via its association with CK2 and PKD kinases, respectively, Component of the COP9 signalosome complex (CSN) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MOV34-34KD CSN6 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
COPS6 Conjugated |
| Short name: |
FITC Conjugated, COPS6 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, COPS6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21749 |
| Gene: |
COPS6 |
More about : COPS6 |
| Long gene name: |
COP9 signalosome subunit 6 |
| Synonyms gene name: |
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) |
| Synonyms name: |
34 kD) , COP9 subunit 6 (MOV34 homolog |
| Locus: |
7q22, 1 |
| Discovery year: |
2003-10-28 |
| GenBank acession: |
BC002520 |
| Entrez gene record: |
10980 |
| Pubmed identfication: |
12477932 |
| RefSeq identity: |
NM_006833 |
| Classification: |
COP9 signalosome |
| Havana BLAST/BLAT: |
OTTHUMG00000154632 |