| Long name: |
COPS6 Primary Polyclonal Antibody |
| Also known as: |
COPS6 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
COPS6 |
| Specificity: |
This is a highly specific antibody against COPS6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human COPS6 |
| Gene ID number: |
10980 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CSA or DDB2, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, Has some glucocorticoid receptor-responsive activity, ITPK1 and IRF8, IkappaBalpha/NFKBIA, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, The complex is also involved in phosphorylation of p53/TP53, a complex involved in various cellular and developmental processes, c-jun/JUN, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, possibly via its association with CK2 and PKD kinases, respectively, Component of the COP9 signalosome complex (CSN) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
34 kD, 34 kD, COP9 complex S6, subunit 6, COP9 constitutive photomorphogenic, COP9 signalosome complex subunit 6, COP9 signalosome subunit 6, COP9 subunit 6 MOV34 homolog, CSN6, CSN6_HUMAN, JAB1 containing signalosome subunit 6, JAB1-containing signalosome subunit 6, MOV34 homolog, MOV34 homolog, MOV34-34KD, SGN6, Sgn3, Signalosome subunit 6, VIP/MOV34, Vpr interacting protein, Vpr-interacting protein, cops6, hVIP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
COPS6 |
| Short name: |
COPS6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
COPS6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21749 |
| Gene: |
COPS6 |
More about : COPS6 |
| Long gene name: |
COP9 signalosome subunit 6 |
| Synonyms gene name: |
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) |
| Synonyms: |
MOV34-34KD CSN6 |
| Synonyms name: |
34 kD) , COP9 subunit 6 (MOV34 homolog |
| Locus: |
7q22, 1 |
| Discovery year: |
2003-10-28 |
| GenBank acession: |
BC002520 |
| Entrez gene record: |
10980 |
| Pubmed identfication: |
12477932 |
| RefSeq identity: |
NM_006833 |
| Classification: |
COP9 signalosome |
| Havana BLAST/BLAT: |
OTTHUMG00000154632 |