| Long name: |
ALEXA FLUOR 647 Conjugated, LC3 Polyclonal Antibody |
| Also known as: |
Anti-LC3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LC3 |
| Specificity: |
This is a highly specific antibody against LC3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
27-59/121 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LC3 |
| Gene ID Number: |
81631, 84557 |
| Swiss Prot: |
Q9GZQ8, Q9H492 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway, Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation, Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MAP1BLC3 MAP1ALC3 LC3 LC3A ATG8E |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the LC3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
LC3 |
| Short name: |
LC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, LC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6838 |
| Gene: |
MAP1LC3A |
More about : MAP1LC3A |
| Long gene name: |
microtubule associated protein 1 light chain 3 alpha |
| Locus: |
20q11, 22 |
| Discovery year: |
2000-06-29 |
| Entrez gene record: |
84557 |
| Pubmed identfication: |
8833088 17580304 |
| RefSeq identity: |
NM_181509 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000032306 |