| Long name: |
LC3 Primary Polyclonal Antibody |
| Also known as: |
LC3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
LC3 |
| Specificity: |
This is a highly specific antibody against LC3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
27-59/121 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LC3 |
| Gene ID number: |
81631, 84557 |
| Swiss Prot: |
Q9GZQ8, Q9H492 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway, Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation, Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 1, MAP1 light chain 3-like protein 2, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 A, MAP1A/MAP1B light chain 3 B, Microtubule-associated protein 1 light chain 3 alpha Microtubule-associated proteins 1A/1B light chain 3B LC3B: Autophagy-related protein LC3 B, Microtubule-associated protein 1 light chain 3 beta, LC3A: Microtubule-associated proteins 1A/1B light chain 3A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LC3 |
| Short name: |
LC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6838 |
| Gene: |
MAP1LC3A |
More about : MAP1LC3A |
| Long gene name: |
microtubule associated protein 1 light chain 3 alpha |
| Synonyms: |
MAP1BLC3 MAP1ALC3 LC3 LC3A ATG8E |
| Locus: |
20q11, 22 |
| Discovery year: |
2000-06-29 |
| Entrez gene record: |
84557 |
| Pubmed identfication: |
8833088 17580304 |
| RefSeq identity: |
NM_181509 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000032306 |