| Long name: |
ALEXA FLUOR 488 Conjugated, CD36 Polyclonal Antibody |
| Also known as: |
Anti-CD36 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD36 |
| Specificity: |
This is a highly specific antibody against CD36 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
360-400/472 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD36 |
| Gene ID Number: |
948 |
| Swiss Prot: |
P16671 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As a coreceptor for TLR4-TLR6 heterodimer, Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport, CXCL2 and CCL9 cytokines, Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes, May function as a cell adhesion molecule, Receptor for thombospondins, THBS1 AND THBS2, Upon ligand binding, and CCL5 cytokine, anionic phospholipids and oxidized low-density lipoprotein (oxLDL), as well as IL1B secretion, leading to NF-kappa-B-dependent production of CXCL1, mediating their antiangiogenic effects, promotes inflammation in monocytes/macrophages, rapidly induces the formation of a heterodimer of TLR4 and TLR6, such as oxLDL or amyloid-beta 42, thrombospondin, via MYD88 signaling pathway, via TICAM1 signaling pathway, which is internalized and triggers inflammatory response, Binds to collagen |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
SCARB3 GPIV FAT GP4 GP3B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CD36 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CD36 |
| Short name: |
CD36 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CD36 molecule (thrombospondin receptor) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BDPLT10 and CHDS7 and FAT and GP3B and GP4 and GPIV and PASIV and SCARB3, CD36 and IDBG-24023 and ENSG00000135218 and 948, Cd36 and IDBG-136838 and ENSMUSG00000002944 and 12491, Extracellular, TAP-dependent and biological process this GO :0002576 and platelet degranulation and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0005041 and low-density lipoprotein receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006910 and pha this GO cytosis, engulfment and biological process this GO :0060907 and positive regulation of macrophage cytokine production and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070892 and lipoteichoic acid receptor activity and molecular function this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071447 and cellular response to hydroperoxide and biological process this GO :0071813 and lipoprotein particle binding and molecular function this GO :2000121 and regulation of removal of superoxide radicals and biological process this GO :2000334 and positive regulation of blood microparticle formation and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, lipoprotein particle binding, recognition and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008035 and high-density lipoprotein particle binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010886 and positive regulation of cholesterol storage and biological process this GO :0015911 and plasma membrane long-chain fatty acid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019915 and lipid storage and biological process this GO :0019934 and cGMP-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030194 and positive regulation of blood coagulation and biological process this GO :0030301 and cholesterol transport and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034381 and plasma lipoprotein particle clearance and biological process this GO :0034383 and low-density lipoprotein particle clearance and biological process this GO :0035634 and response to stilbenoid and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0042992 and negative regulation of transcription factor import into nucleus and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044539 and long-chain fatty acid import and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0055096 and low-density lipoprotein particle mediated signaling and biological process this GO :0060100 and positive regulation of pha this GO cytosis, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005041 : low-density lipoprotein receptor activity, this GO :0005041 : low-density lipoprotein receptor activity and also this GO :0005515 : protein binding and also this GO :0008035 : high-density lipoprotein particle binding and also this GO :0008289 : lipid binding and also this GO :0030169 : low-density lipoprotein particle binding and also this GO :0050431 : transforming growth factor beta binding and also this GO :0070053 : thrombospondin receptor activity and also this GO :0070892 : lipoteichoic acid receptor activity and also this GO :0071813 : lipoprotein particle binding, this GO :0005515 : protein binding, this GO :0008035 : high-density lipoprotein particle binding, this GO :0008289 : lipid binding, this GO :0030169 : low-density lipoprotein particle binding, this GO :0050431 : transforming growth factor beta binding, this GO :0070053 : thrombospondin receptor activity, this GO :0070892 : lipoteichoic acid receptor activity, this GO :0071813 : lipoprotein particle binding, CD36 molecule (thrombospondin receptor) |
| Identity: |
1663 |
| Gene: |
CD36 |
More about : CD36 |
| Long gene name: |
CD36 molecule |
| Synonyms gene name: |
CD36 antigen (collagen type I receptor, thrombospondin receptor) CD36 molecule (thrombospondin receptor) |
| Locus: |
7q21, 11 |
| Discovery year: |
1993-06-04 |
| GenBank acession: |
Z32770 |
| Entrez gene record: |
948 |
| Pubmed identfication: |
7503937 |
| RefSeq identity: |
NM_001001547 |
| Classification: |
CD molecules Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000155383 |