| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CD36 |
| Specificity: |
This antibody reacts specifically with CD36 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse CD36 |
| Gene ID: |
12491 |
| Swiss Prot: |
Q08857 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
As a coreceptor for TLR4-TLR6, Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport (By similarity), CXCL2 and CCL9 cytokines, Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes, May function as a cell adhesion molecule, Receptor for thombospondins, THBS1 AND THBS2, Upon ligand binding, and CCL5 cytokine, anionic phospholipids and oxidized low-density lipoprotein (oxLDL), as well as IL1B secretion, leading to the NF-kappa-B-dependent production of CXCL1, mediating their antiangiogenic effects (By similarity), promotes inflammation in monocytes/macrophages, rapidly induces the formation of a heterodimer of TLR4 and TLR6, such as oxLDL or amyloid-beta 42 binding, thrombospondin, via MYD88 signaling pathway, via TICAM1 signaling pathway, which is internalized and triggers inflammatory signals, Binds to collagen |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SCARB3 GPIV FAT GP4 GP3B |
| Also known as: |
CD36 Polyclonal Antibody |
| Other name: |
Anti-CD36 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CD36 |
| Short name: |
Anti-CD36 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CD36 molecule (thrombospondin receptor) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BDPLT10 and CHDS7 and FAT and GP3B and GP4 and GPIV and PASIV and SCARB3, CD36 and IDBG-24023 and ENSG00000135218 and 948, Cd36 and IDBG-136838 and ENSMUSG00000002944 and 12491, Extracellular, TAP-dependent and biological process this GO :0002576 and platelet degranulation and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0005041 and low-density lipoprotein receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006910 and pha this GO cytosis, engulfment and biological process this GO :0060907 and positive regulation of macrophage cytokine production and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070892 and lipoteichoic acid receptor activity and molecular function this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071447 and cellular response to hydroperoxide and biological process this GO :0071813 and lipoprotein particle binding and molecular function this GO :2000121 and regulation of removal of superoxide radicals and biological process this GO :2000334 and positive regulation of blood microparticle formation and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, lipoprotein particle binding, recognition and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008035 and high-density lipoprotein particle binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010886 and positive regulation of cholesterol storage and biological process this GO :0015911 and plasma membrane long-chain fatty acid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019915 and lipid storage and biological process this GO :0019934 and cGMP-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030194 and positive regulation of blood coagulation and biological process this GO :0030301 and cholesterol transport and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034381 and plasma lipoprotein particle clearance and biological process this GO :0034383 and low-density lipoprotein particle clearance and biological process this GO :0035634 and response to stilbenoid and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0042992 and negative regulation of transcription factor import into nucleus and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044539 and long-chain fatty acid import and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0055096 and low-density lipoprotein particle mediated signaling and biological process this GO :0060100 and positive regulation of pha this GO cytosis, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005041 : low-density lipoprotein receptor activity, this GO :0005041 : low-density lipoprotein receptor activity and also this GO :0005515 : protein binding and also this GO :0008035 : high-density lipoprotein particle binding and also this GO :0008289 : lipid binding and also this GO :0030169 : low-density lipoprotein particle binding and also this GO :0050431 : transforming growth factor beta binding and also this GO :0070053 : thrombospondin receptor activity and also this GO :0070892 : lipoteichoic acid receptor activity and also this GO :0071813 : lipoprotein particle binding, this GO :0005515 : protein binding, this GO :0008035 : high-density lipoprotein particle binding, this GO :0008289 : lipid binding, this GO :0030169 : low-density lipoprotein particle binding, this GO :0050431 : transforming growth factor beta binding, this GO :0070053 : thrombospondin receptor activity, this GO :0070892 : lipoteichoic acid receptor activity, this GO :0071813 : lipoprotein particle binding, CD36 molecule (thrombospondin receptor) |
| Identity: |
1663 |
| Gene: |
CD36 |
More about : CD36 |
| Long gene name: |
CD36 molecule |
| Synonyms gene name: |
CD36 antigen (collagen type I receptor, thrombospondin receptor) CD36 molecule (thrombospondin receptor) |
| Locus: |
7q21, 11 |
| Discovery year: |
1993-06-04 |
| GenBank acession: |
Z32770 |
| Entrez gene record: |
948 |
| Pubmed identfication: |
7503937 |
| RefSeq identity: |
NM_001001547 |
| Classification: |
CD molecules Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000155383 |