| Long name: |
ALEXA FLUOR 647 Conjugated, GHRHR Polyclonal Antibody |
| Also known as: |
Anti-GHRHR PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GHRHR |
| Specificity: |
This is a highly specific antibody against GHRHR |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GHRHR |
| Gene ID Number: |
2692 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation, GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS), GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH, In addition, Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1, also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH), reproduction and immune function, this signalling pathway may have direct action in fetal/placental development, GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GHRHR Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GHRHR |
| Short name: |
GHRHR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GHRHR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4266 |
| Gene: |
GHRHR |
More about : GHRHR |
| Long gene name: |
growth hormone releasing hormone receptor |
| Locus: |
7p14, 3 |
| Discovery year: |
1993-06-22 |
| Entrez gene record: |
2692 |
| Pubmed identfication: |
7680413 7514564 |
| Classification: |
Glucagon receptor family |
| Havana BLAST/BLAT: |
OTTHUMG00000152801 |