| Long name: |
Histone H2A, X (Ubiquityl Lys119) Antibody |
| Also known as: |
Histone H2A, X (Ubiquityl Lys119) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Histone H2A, X Ubiquityl Lys119 |
| Specificity: |
This modification site is homologous to that of Lys119 in Rat, This is a highly specific antibody against Histone H2A, X Ubiquityl Lys119 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
90-130/143 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ubiquityl Histone H2A, X (Lys119) |
| Gene ID number: |
3014 |
| Swiss Prot: |
P16104 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, Variant histone H2A which replaces conventional H2A in a subset of nucleosomes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
H2A, H2A/X, H2AFX, Histone H2A, Histone H2AX, H2AX, X, X |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Histone H2A, X (Ubiquityl Lys119) |
| Short name: |
Histone H2A, X (Ubiquityl Lys119) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Histone H2A, X (Ubiquityl Lys119) (Antibody to) |
| Alternative technique: |
antibodies |