| Long name: |
Cy5, 5 Conjugated, MLLT11 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MLLT11 |
| Specificity: |
This is a highly specific antibody against MLLT11 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human MLLT11 |
| Gene ID number: |
10962 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also, Based on the expression patterns of MLLT11, Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10% of patients with acute lymphoblastic leukemia (ALL) and 5% of patients with acute myeloid leukemia (AML), Finally, MLLT11, MLLT11 has been shown to be differentially expressed in highly metastatic cells, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system, Most patients affected are less than 1 year of age, Such findings suggest a role of MLLT11 in tumorigenesis, also known as mixed-lineage leukemia translocated to 11 or AF1q, expressed in embryonic brain cortex, in comparison with non-metastatic parent cells, is a 90 amino acid MLL fusion partner, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML), The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
AF1Q |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
MLLT11 Conjugated |
| Short name: |
Conjugated, MLLT11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
11 (Antibody to), Drosophila), cyanine 5, translocated to, 5 coupled, myeloid/lymphoid and mixed-lineage leukemia (trithorax homolog |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
11, AF1Q, DNA-templated and biological process this GO :0051901 and positive regulation of mitochondrial depolarization and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, Drosophila), MLLT11 and IDBG-244926 and ENSG00000213190 and 10962, MLLT11 and IDBG-633245 and ENSBTAG00000015369 and 539519, Mllt11 and IDBG-171976 and ENSMUSG00000053192 and 56772, molecular_function, multiple, this GO :0003674 and molecular function and molecular function this GO :0005622 and intracellular and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045893 and positive regulation of transcription, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function, translocated to, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog |
| Identity: |
16997 |
| Gene: |
MLLT11 |
More about : MLLT11 |
| Long gene name: |
11 , myeloid/lymphoid or mixed-lineage leukemia, translocated to |
| Synonyms gene name: |
11 , Drosophila), myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, translocated to |
| Synonyms name: |
ALL1 fused gene from chromosome 1q |
| Locus: |
1q21, 3 |
| Discovery year: |
2005-05-23 |
| GenBank acession: |
BC006471 |
| Entrez gene record: |
10962 |
| Pubmed identfication: |
7833468 |
| RefSeq identity: |
NM_006818 |
| Havana BLAST/BLAT: |
OTTHUMG00000035160 |