| Long name: |
Cy5 Conjugated, ABL1+2(Tyr393+439) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ABL1+2Tyr393+439 |
| Specificity: |
This is a highly specific antibody against ABL1+2Tyr393+439 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr393+439 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Abl around the phosphorylation site of Tyr393 |
| Gene ID number: |
25 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activity of c-Abl protein is negatively regulated by its SH3 domain, The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, The t(9, [provided by RefSeq], and deletion of the SH3 domain turns ABL1 into an oncogene, and stress response, cell adhesion, cell division, suggesting a cell cycle function for ABL1, with alternatively spliced first exons spliced to the common exons 2-11, 22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia, The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
JTK7 c-ABL p150 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ABL1+2(Tyr393+439) Conjugated |
| Short name: |
Conjugated, ABL1+2(Tyr393+439) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, non-receptor tyrosine kinase+2(Tyr393+439) (Antibody to), c-abl oncogene 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ABL and bcr/abl and c-ABL and c-ABL1 and JTK7 and p150 and v-abl, ABL1 and IDBG-639939 and ENSBTAG00000017976 and 540876, ABL1 and IDBG-89599 and ENSG00000097007 and 25, Abl1 and IDBG-158216 and ENSMUSG00000026842 and 11350, DNA-templated and biological process this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006914 and autophagy and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, non-receptor tyrosine kinase, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003785 and actin monomer binding and molecular function this GO :0004515 and nicotinate-nucleotide adenylyltransferase activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006298 and mismatch repair and biological process this GO :0006355 and regulation of transcription, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0003677 : DNA binding and also this GO :0003785 : actin monomer binding and also this GO :0004515 : nicotinate-nucleotide adenylyltransferase activity and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0003677 : DNA binding, this GO :0003785 : actin monomer binding, this GO :0004515 : nicotinate-nucleotide adenylyltransferase activity, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0017124 : SH3 domain binding, this GO :0019904 : protein domain specific binding, this GO :0019905 : syntaxin binding, this GO :0030145 : manganese ion binding, this GO :0051019 : mitogen-activated protein kinase binding, this GO :0070064 : proline-rich region binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017124 : SH3 domain binding and also this GO :0019904 : protein domain specific binding and also this GO :0019905 : syntaxin binding and also this GO :0030145 : manganese ion binding and also this GO :0051019 : mitogen-activated protein kinase binding and also this GO :0070064 : proline-rich region binding, transferring phosphorus-containing groups and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030100 and regulation of endocytosis and biological process this GO :0030145 and manganese ion binding and molecular function this GO :0030155 and regulation of cell adhesion and biological process this GO :0031252 and cell leading edge and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042770 and signal transduction in response to DNA damage and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051019 and mitogen-activated protein kinase binding and molecular function this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0070064 and proline-rich region binding and molecular function this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :2000145 and regulation of cell motility and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process this GO :2001020 and regulation of response to DNA damage stimulus and biological process, c-abl oncogene 1 |
| Identity: |
76 |
| Gene: |
ABL1 |
More about : ABL1 |
| Long gene name: |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
| Synonyms gene: |
ABL |
| Synonyms gene name: |
non-receptor tyrosine kinase , receptor tyrosine kinase c-abl oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1 c-abl oncogene 1 |
| Locus: |
9q34, 12 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M14752 |
| Entrez gene record: |
25 |
| Pubmed identfication: |
1857987 12626632 |
| RefSeq identity: |
NM_007313 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020813 |
| Locus Specific Databases: |
LRG_769 |