| Long name: |
Cy7 Conjugated, Ecadherin binding protein E7 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ecadherin binding protein E7 |
| Specificity: |
This is a highly specific antibody against Ecadherin binding protein E7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CBLL1/Ecadherin binding protein E7 |
| Gene ID number: |
79872 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions, More specifically, Via its role as an E-cadherin regulator, also known as HAKAI (meaning â, in Japanese), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger, or RNF188 (RING finger protein 188), thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts, upon activation of c-Src, &euro, &euro, &tilde, &trade, CBLL1, destructionâ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
CasBrM murine ecotropic retroviral transforming sequencelike 1, Casitas B-lineage lymphoma transforming sequence-like protein 1, Casitas B-lineage lymphoma-like 1, Casitas B-lineage lymphoma-transforming sequence-like protein 1, E3 ubiquitin-protein ligase Hakai, Ecadherin binding protein E7, FLJ23109, HAKAI, HAKAI_HUMAN, MGC163401, MGC163403, OTTHUMP00000206720, OTTHUMP00000206722, OTTHUMP00000206724, RING finger protein 188, RNF188, cbll1, c-Cbl-like protein 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
Ecadherin binding protein E7 Conjugated |
| Short name: |
Conjugated, Ecadherin binding protein E7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, Ecadherin binding protein E7 (Antibody to) |
| Alternative technique: |
antibodies |