| Long name: |
Biotin Conjugated, Jarid1C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Jarid1C |
| Specificity: |
This is a highly specific antibody against Jarid1C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Jarid1C/KDM5C |
| Gene ID number: |
11184 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period, MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements, facial dysmorphism, seizures, thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3, Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) , Tissue specificity:br> |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
DXS1272E, Histone demethylase JARID1C, JmjC domain containing protein SMCX, Jumonji AT rich interactive domain 1C, Jumonji/ARID domain-containing protein 1C, KDM5C, KDM5C_HUMAN, Lysine K specic demethylase 5C, Lysine-specic demethylase 5C, MRXJ, MRXSCJ, MRXSJ, Protein SmcX, Protein Xe169, Selected cDNA on X, SmcX protein, Smcx homolog X chromosome, Smcy homolog X linked, XE169, Xe169 protein, Xe169 protein, rbp2 like protein, SmcX protein |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Jarid1C Conjugated |
| Short name: |
Conjugated, Jarid1C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Jarid1C (Antibody to) |
| Alternative technique: |
antibodies |